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Sharon G, Sampson TR, Geschwind DH, Mazmanian SK

Polyphenols as antitumor agents targeting key players in cancer-driving signaling pathways

A.NeumannC

Convergent ERK1/2, p38 and JNK mitogen activated protein kinases (MAPKs) signalling mediate catecholoestradiol-induced proliferation of ovine uterine artery endothelial cells

Moreover, achieving signaling bias through allosteric modulation could enhance the safety of M1-mAChR drugs, making it a key consideration in the development of M1-mAChR allosteric ligands