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(2004) 109(23 Suppl 1):Iii2732

42 In this paragraph, we try to explain the roles of both SCs and collagen-induced molecules

CSCs exhibit a resistance to radiation and chemotherapy due to the upregulation of numerous detoxifying enzymes, such as superoxide dismutase 2, glutathione peroxidases and heme oxygenase 1, that increase drug efflux and DNA repair capabilities (44,67,68)