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The volume of distribution after intravenous administration is 211.9 186.6 L

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Among these mechanisms, the action of glial cells upon lesion and regeneration has become a prominent research topic, helped not only by the discovery of glia as targets of autoantibodies, but also by their role on CNS homeostasis and neuroinflammation

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Genetic deletion of Aqp4 in mouse models reduces A efflux by approximately 55%, accelerating plaque deposition [405, 406]

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