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70 Over 74% of individuals entering treatment for drug addiction had clinical signs of nutrient deficiency in one study by Nazrul et al., 71 with the most pronounced risk for deficiency being in the antioxidant vitamins A, E, and C and in amino acids

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DM conditions have various cellular environments, such as enhanced oxidative stress, AGEs, neuronal damage conditions, and decreased neuronal growth, synaptic plasticity, and neurogenesis

Finally, oxidative stress may lead to incorrect formation of neuronal connections and/or firing patterns during neurodevelopment

7 It also has been suggested that hyperhomocysteinemia in combination with the Factor V Leiden mutation (R506Q) results in resistance to activation by protein C, thereby facilitating a predisposition to thrombosis

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