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Thus, specific targeting of IGF-1R signaling post development may prove to be the best approach to achieve the benefits of low growth signals on healthspan and aging, without the potential unwanted side effects of combined adult-onset GH/IGF-1 deficiency

Zambrano S, Blanca AJ, Ruiz-Armenta MV, Miguel-Carrasco JL, Arvalo M, Mate A, Vzquez CM (2014) L-carnitine attenuates the development of kidney fibrosis in hypertensive rats by up-regulating PPAR-

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