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Patients who chronically under-hydrate (fewer than 2 litres daily) show blunted metabolic responses to supplementation

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This raises questions about dosage adjustments over time that the standard escalation charts do not address

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This and additional blind studies suggest that this restoration of motor function is likely permanent having been observed out to three months post-lesioning

20 units = 0.2mL 100mg/mL = 20mg per injection