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further revealed the mechanism of the mitochondrion-localized AMPK (mitoAMPK) response to local energy dynamics

Although debatable, bladder tissue of non-Hunner type IC patients presented predominant fibrosis and mast cell infiltration in our previous study 12

doi:10.21037/apm-20-702 42 Watford M

Amino Acids 51:11031127

Second, given that the activation of GSR and TXNRD1 are involved in ROS elimination, if the LCS3-triggered lethality of VRK2-KO PC cells could be attributed to inhibiting the activity of both GSR and TXNRD1, then the level of ROS generated by LCS3 should have been much higher than those produced by the treatment of the TXNRD1 inhibitor auranofin