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"Nicotinamide N-methyltransferase: More than a vitamin B3 clearance enzyme." Trends in Endocrinology & Metabolism (2017)

Specific data are shown in Table 5

[2] Oral ingestion of large amounts of B12 is highly unlikely to cause an issue, as not all B12 survives this process

Legitimate access runs through a licensed physician and a compounding pharmacy, under medical supervision

Men with naturally high aromatase activity or those whose estrogen rises disproportionately to testosterone increases face greater risk

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