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Abstract Parkinsons disease (PD) is the second most common neurodegenerative disease, the main pathological hallmark of which is the accumulation of -synuclein (-syn) and the formation of filamentous aggregates called Lewy bodies in the brainstem, limbic system, and cortical areas

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First, the unique physicochemical properties of nanomaterials (e.g., size, shape, surface charge) may result in biological behaviors that differ significantly from traditional drugs, necessitating a reassessment of their safety, efficacy, and toxicological characteristics by regulatory agencies

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4 Lysosome & Autophagy Several autophagy-related genes modulate ferroptosis by autophagic degradation of cellular iron storage proteins

Tocopherols in the leaves were quantified using high-performance liquid chromatography (HPLC) with Dimethyl tocol serving as an internal standard, as outlined by AbdElgawad et al