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High concentrations of cytotoxic BAs (e.g., DCA) can drive microbial transcriptional reprogramming, including upregulation of efflux pumps and stress response genes, and alterations in core metabolism and BA-modifying enzyme expression (122)

Retrieved from d90f7ee19 11/17/14 Jefferson Lab

Many pharmacokinetics models do not succeed in truly describing the disposition of paclitaxel in the body of human beings

To our knowledge, no large-scale microbiome profiling study has directly compared comorbid patients (meeting diagnostic criteria for both conditions simultaneously) against single-disease and healthy control groups within the same dataset

Impaired pulmonary function as a risk factor for mortality

S., Crisler, W