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The development of GC involves multiple factors, including Helicobacter pylori and Epstein-Barr virus infections, exposure to carcinogens, suppression of tumor suppression genes, abnormal cell apoptosis, and disruption of cell cycle regulation

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(7) Sarah Wrigley, Donia Arafa, and Daniela Tropea (2017) Insulin-Like Growth Factor 1: At the Crossroads of Brain Development and Aging Frontiets in Cellular Neuroscience, 2017 Feb 1, Volume 11, Page 14

Mice fed a fiber-deficient diet showed a significant reduction in Bacteroidota (basonym Bacteroidetes) and an increase in Pseudomonadota (basonym Proteobacteria), which damaged the intestinal barrier and decreased the production of SCFAs, resulting in cognitive decline (Shi et al., 2021)