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NBDHEX simultaneously activates JNK and TRAF2, interfering with the effect of GST via two different pathways, leading to cell-cycle arrest and cell death

Its copper binding property also contributes to its chemical stability, making it suitable for use in experimental and laboratory procedures

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Clin Endocrinol 44(5):533539 Murray PG, Clayton PE (2000) Disorders of growth hormone in childhood Nashiro K et al (2017) Brain structure and function associated with younger adults in growth hormone receptor-deficient humans

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