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if the contact time is inadequate, impurity ions within the resins cannot be effectively displaced, resulting in a significantly compromised regeneration outcome

Asymmetric dimethylarginine (ADMA), a recognized NOS endogenous competitive inhibitor, also plays a role in the pathogenesis of lowering NO generation in several disorders [63]

Masutani M

Metabolic dysfunction-associated steatotic liver disease (MASLD) MASLD is the most prevalent CLD globally, with a global prevalence of approximately 32% (estimated in 2022) and is strongly associated with obesity, dyslipidemia, and insulin resistance 46,47

Int J stem Cells 7:8797 Forbes SJ, Newsome PN (2012) New horizons for stem cell therapy in liver disease