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4 Current approaches for cancer therapy, their impact on the TME, and post-cancer treatment 4.1 Chemotherapy Chemotherapy is typically used for advanced cancers, particularly when metastasis has occurred

This demonstrates that crotonylation promotes glycolytic reprogramming by stabilizing PKM2 expression

doi: 10.1186/s40659-021-00347-1 288 ZhubiA.ChenY.DongE.CookE

Clinical practice guideline: evaluation of the neck mass in adults

doi: 10.3389/fphar.2021.622841 84 ChenLWangLAoWChenYLiSHuangZet al

Among these, esculetin (ESC), a naturally occurring coumarin derivative also known as 6,7-dihydroxycoumarin, distinguishes itself by a comprehensive spectrum of biological activities