Current areas of scientific investigation include cellular integrity and cytoprotective signaling studies, endothelial and vascular pathway research, inflammatory signaling pathway analysis, peptide stability and degradation studies, cellular stress response research, and biochemical signaling network evaluation
HIF stabilizers have been demonstrated in phase 2 and phase 3 clinical trials to be equally effective as ESA in treating renal anemia (251)
doi: 10.1111/jocd.16544 24 SchallreuterKUElwarySMGibbonsNCRokosHWoodJM
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Curcumin can also facilitate anti-proliferation and reduce the migration property of PC stem cells by modulating miRNAs
Toole JF, Malinow MR, Chambless LE, et al