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Using an HCT116 5FUCRISPR screen, in which cells infected with the Gecko v1 library were cultured with or without 5FU for 11 days (Fig

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A portion of the resulting acid extract (0.5 ml) was added to a tube with 50 l solution containing 15 mmol/L -glutamyl-glutamate (-Glu-Glu) as the internal standard

In addition to hormonal mechanisms, human data suggest sex-specific responses to ketogenic therapy for weight loss, with men often showing greater reductions in body mass and inflammation levels than women [73,89]

Aronne founded and directs the Comprehensive Weight Control Center, a state-of-the-art multidisciplinary obesity research and treatment facility, and has written three books including his most recent, Change Your Biology Diet: The Proven Program for Lifelong Weight Loss

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