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If water retention becomes severe, it may be necessary to adjust the dosage or frequency of administration

They can cause side effects and, in some cases, allergic reactions

COA Summary Purity 98.0% Testing Method HPLC / ESI-MS Lab Type ISO-Accredited Availability On Request HPLC purity verification Mass spectrometry confirmation Independent third-party lab Lot-specific documentation Storage Store lyophilized compound at 20C or below

That basically means no one knows whether the vitamin helps or hurts, or even if deficiencies increase your risk

Side effects: Worse sleep quality

Sleep is even critical for mood regulation, which is why studies link insufficient sleep with increased levels of anxiety and depression