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Likewise, TGF-1 suppressed the expression of GCLC (no effect on GCLM) and lowered GSH levels in rat hepatic stellate cells (HSCs), which facilitated fibrogenesis (Fu et al., 2008)

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In the light of ideas put forward by Parr et al., other new concepts contributing very important information about the response of a chemical species when it reacts with other chemical reagents were defined by several authors, including Gazquez [8-17]