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Subsequently, we found that the thiol and amine can be added simultaneously to the BDA intermediate to still generate the same 3-thio N -pyrrole heterocycle 2a because of the high nucleophilicity of thiols as compared to amines (entry 3, Fig

When administering intramuscular injections of peptides, the upper arm, and the buttocks are typically the best injection sites

[4] In patients with cyanide poisoning, hydroxocobalamin also acts as an antidote by binding to cyanide ions with high affinity to form nontoxic cyanocobalamin

Over 100 types of RNA modifications have been identified, including N6-methyladenine (m 6 A) and N1-methyladenine, primarily in rRNA and tRNA 146

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