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OS develops due to a disproportion between the synthesis and accumulation of the free radicals referred to as ROS and reactive nitrogen species (RNS)

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23 In fact, oxidative stress negatively regulates the expression of -Catenin could attenuate the Wnt pathway

In vitro and in vivo studies showed the nanoconjugate DDS to have excellent anti-tumor activity while also exhibiting significantly lower toxic side effects [90]

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In adults with type 2 diabetes, the higher doses produced strong weight loss alongside HbA1c reductions of up to ~2.4% versus placebo [3]