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NNMT has been explored as a target in obesity, insulin resistance, and age-related metabolic decline, supporting the rationale for translational research into body composition and performance contexts (Kannt & Pfenninger, Frontiers in Physiology )

We first conducted a targeted metabolite assay using isolated whole brains of male and female Tbx1 +/ and WT mice (Table S1, Group 1 in Fig S1C)

[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Foitzik K., Lindner G., Mueller-Roever S., Maurer M., Botchkareva N., Botchkarev V., Handjiski B., Metz M., Hibino T., Soma T., et al