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The largest Phase 2b trial used 0.25, 0.5, and 1 mg/day orally for 24 weeks

Boosters are intended to return the level of protection to the vaccine's optimal level

If nausea onset coincides with 5-amino-1MQ introduction but tirzepatide dose was stable for 4+ weeks prior, the new compound is the likely culprit

doi:10.1093/ajcn/80.3.539 Lee JE, Jacques PF, Dougherty L, et al

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