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Thus, when the L subunit is affected, RBCs contain only M 4 PFK homotetramers and are partially PFK deficient

Furthermore, GSH synthesis can also be amplified by Nrf2-mediated GCLC and glutathione synthetase upregulation[150]

Khan, N.A

Therefore, understanding the underlying mechanisms of tamoxifen resistance in breast cancer is critical to reducing the prevalence of treatment resistance in breast cancer and associated mortality