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[38] Prevention of neurotransmitter-induced hyperexcitability of nerve cells via Kv7.2 channel and AKAP5 may also contribute to its mechanism

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Conclusion Although defined as non-essential, L-serine plays critical roles in redox homeostasis, lipid metabolism, immune function, and mucosal defense against pathogens, highlighting its importance in maintaining intestinal homeostasis

Acknowledgements Thanks to Guoqiang Chang and Cuijuan Shi from the Tianjin Neurological Institute, Tianjin Medical University General Hospital, and Tao Han from Xinxiang Medical University for their selfless help in this study