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NAC (N-acetyl cysteine) : As a precursor for the bodys glutathione production, adding NAC supplementation to ones diet can yield a four fold increase in glutathione synthesis

However, it was found that cisplatin-induced apoptosis is related to disbalance in the mGSH/GSSG ratio, decrease in NADPH(H + ) content, and oxidative damage of cardiolipin and aconitase, which disturbs the functioning of mitochondria and activates caspase-3 [78, 79]

Vincent, J.L

10.1016/j.freeradbiomed.2020.02.027 368 Van AckerZ

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Cuproptosis: mechanisms and links with cancers [J]