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The lower ratio in primed cells could partially suppress TET/JMJ demethylation, helping maintain the higher DNA/histone methylation characteristic of primed pluripotency, whereas the higher ratio in naive cells permits more active demethylation and a hypomethylated state

[DOI] [PubMed] [Google Scholar] [105].Porkert M, Sher S, Reddy U, Cheema F, Niessner C, Kolm P, Jones DP, Hooper C, Taylor WR, Harrison D, Quyyumi AA

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B R Nascimento reports grants or contracts from CNPq (Conselho Nacional de Desenvolvimento Cientfico e Tecnolgico Research Productivity Grant number 312382/2019-7), Edwards Lifesciences Foundation Research Grant for Global Health (Improving the Prevention and Detection of Heart Valve Disease Across the Lifespan, 2023) FAPEMIG (Fundao de Amparo a Pesquisa do Estado de Minas Gerais Research Grant number APQ-000627-20

The immune response triggered by periodontal tissue inflammation leads to the release of a large number of active substances, exacerbating the imbalance of the antioxidant system and tissue damage

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