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In one sentence, the mechanism is receptor-mediated: GHRP binding to GHS-R1a activates a Gq/11-coupled phospholipase C cascade that mobilises intracellular calcium and triggers exocytosis of stored GH from the anterior pituitary, independent of hypothalamic GHRH signalling

B12 injections are very safe, even at higher doses, when given by a trained provider

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This includes the reversible conversions of fumarate to malate and citrate to isocitrate, as well as the oxidation of acetyl-CoA

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