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Several risk factors such as aging, smoking, and oxidative stress contribute to HHcy severity [10, 11] contributing to severe pathologies, namely, neurodegenerative disorders (Alzheimers (AD) and Parkinsons disease (PD), dementia, neuropsychiatric illness), thrombosis, cerebrovascular disease, osteoporosis-associated fractures, cardiovascular disease (CVD), and cancer [12,13,14,15,16,17]

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Goossens for her help during monophasic EAE experiments

2024 [Epub ahead of print] 25

347 In addition, protein lactylation affects matrix and cholesterol metabolism within tendinopathy, a condition intricately linked to lactate metabolism

In order to identify the optimum hirudin concentration, 2.5, 12.5, and 20 g/ml thrombin was incubated with increasing concentrations of hirudin (14 nM to 14 M) in activation buffer