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The risks, which range from lowered sperm quality to disrupted endocrine function, make nicotine a poor choice for any man looking to optimize his hormones or health

Cheng CM, Kelley B, Wang J, Strauss D, Eagles DA, Bondy CA

Diabetes 64 , 11931201 (2015)

An increased ratio of succinate to -KG in cancers resulting from impaired succinate dehydrogenase (SDH) activity is related to pervasive DNA hypermethylation, which contributes to the downregulation of key genes implicated in cell differentiation and cancer stages 102