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doi: 10.3390/ijerph18115723 109 PeruzzoloM.CeniG

Fontana 2 and Jonathan Sexton 3 , (1)University of Michigan, (2)University of Michigan Medical Center, Ann Arbor, MI, (3)University of Michigan Medical Center Background: In efforts to develop more physiologic in vitro models of human drug-induced liver injury (DILI), directed differentiation of stem cells towards human liver cells and multicellular human liver organoids (HLOs) have been developed