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Cross-talk between TSC2 and the extracellular matrix controls pulmonary vascular proliferation and pulmonary hypertension

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Absence of lot analytical characterisation : a contaminated or mis-dosed lot can invalidate an entire experimental series Preregistration and ARRIVE 2.0 Modern animal research standards require protocol preregistration (OSF, PreclinicalTrials.eu) with ex ante definition of primary, secondary criteria and exclusion rules

In a more recent study, piperine was found to reduce the complications in infarcted area and restore the integrity of hippocampal gyri by inhibiting autophagy through suppressing the PI3K/AKT/mTOR pathway (Zhang et al., 2022)

For vegetarians and vegans, the best options are vitamin B12 fortified foods including fortified plant milks (soy, oat, almond), fortified nutritional yeast, fortified breakfast cereals, and fortified meat alternatives alongside B12 supplements when dietary intake is insufficient

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