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The calcium-binding affinity of S100 proteins is low in the absence of target proteins, but the affinity is significantly increased by several orders of magnitude in the presence of specific target proteins (35, 36)

Campbell J, Franzen A, Van Landingham C, Lumpkin M, Crowell S, Meredith C, Loccisano A, Gentry R, Clewell H

Weschawalit S, Thongthip S, Phutrakool P, Asawanonda P

doi: 10.1136/jcp.2009.072561 114 KomaroffAL

Additionally, HCA (as Super CitriMaxTM, HCA-SX) enhances the release of 5-HT from rat brain cortex slices in vitro , allowing researchers to elucidate how HCA might reduce hunger (Ohia et al., 2001)

vulgaris aerial parts investigated the plant's hemodynamic efficacy by infusing a 10% solution of the aqueous extract into the segregated transfused mesentery of rats effectively