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mansoni, which was assigned to the action of a metabolite (having the general structure 5, Figure 9) rather than to OPZ itself [58]

doi: 10.1038/onc.2016.304

Progranulin inhibits LPS-induced macrophage M1 polarization via NF-B and MAPK pathways

Future research is warranted to address these challenges and investigate the possibility of synergizing inhibitors of NADPH synthesis for novel combinatorial therapies with current chemotherapeutics