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Documented in animal-model literature for tissue remodeling, GI mucosal barrier signaling, and the cytoprotection paradigm

Embodiments of the invention also comprise one or more steps related to monitoring the effects or outcome of administration in order to evaluate the treatment protocol and/or to adjust the protocol as required or in a manner that is likely to provide more benefit, e.g

This was coincidence with our findings where Propolis and Chlorhexidine groups showed a statistically significant low microleakage which in turn might reflect the good performance of such nanogels as they could perfectly disinfect the prepared cavities without retarding adhesion