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Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses

These drugs may include azathioprine, methotrexate or mycophenolate

PMCID: PMC8509000

Downstream analysis revealed significantly decreased expression of antioxidant proteins Nrf2 and HO-1, accompanied by increased phosphorylation of NF-B, indicating enhanced neuroinflammation and impaired antioxidant defenses