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neither cholera, smallpox, or any malarious disease [is] doing more injury in the world than this poison. [5] Meanwhile, in 1867, the St

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doi: 10.1128/iai.62.9.4015-4020.1994 63 MaykutMO

Development of novel therapeutics targeting mitochondrial metabolism In recent years, an increasing number of mitochondria-targeted therapeutic candidates have entered preclinical development or clinical evaluation, showing promising anti-CRC potential [146] (Table 1)

This suggested that the CD36/MAPK/JNK pathway may play a key role in TMAO-induced foam cell formation ( in vitro study found that different concentrations of TMAO have no effect on the formation of foam cells in mouse macrophages ( The NLRP3 inflammasome is a polyprotein complex formed by the activation of PRRs that was recently reported to be crucial for the development of AS (Hoseini et al., 2018)