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Upon direct binding with cytosolic DNA, cGAS is activated to catalyze the production of cyclic GMP-AMP (cGAMP), leading to the activation of the downstream sensor STING

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Metabolism of glutamate and glutamine in neurons and astrocytes in primary cultures, in , ed.KvammeE

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[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Abdala-Valencia H., Berdnikovs S., Cook-Mills J.M

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