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Figure 2 While depletion of B cells and loss of antibodies is a reported side-effect of Daratumumab treatment, we also observed strong depletion of CD38+ CD8+ T cell subsets that was previously unreported ( Figure 2B ) ( Figure 2B )

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Small observational studies have reported modest weight loss, but these typically lack adequate controls for dietary modification, exercise, and placebo effects

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Randomization of trial participants into treatment groups aims to avoid selection bias and to balance the treatment groups at baseline