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Effects of exercise and low-fat diet on adipose tissue inflammation and metabolic complications in obese mice

Asterisks (*) indicate significant differences (ns, not significant

Adjusted HR for all-cause, cardiovascular and cancer-related mortality was: 1.047 (1.0271.067), 1.017 (0.9731.064) and 1.052 (1.0171.088), each for 10 U/L increase in GGT activity

M.Dias Da SilvaD.CarmoH.CarvalhoF.SilvaJ

In vitro investigations have highlighted the potential of sulforaphane to prevent the loss of oligodendrocytes and axonal damage in multiple sclerosis, by modulating neuroinflammation and oxidative stress (Lim et al., 2016)

In addition, a study conducted in BV2 murine microglia cells, which served as a representative cell specimen for brain microglia, showed that the upregulation of antioxidant/detoxification proteins by SFN was associated with enhanced resistance of microglial cells to heat-induced toxicity and removal of ROS during microglial cell activation (90)