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et al., 2023), but may also influence BIPN by regulating the transcription of the pain biomarker monocyte chemoattractant protein-1 (Zhang and De Koninck, 2006)

Because results build gradually, consistent use over several months is generally recommended before expecting noticeable improvements in the appearance of skin texture, firmness, or fine lines

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However, further studies are needed to confirm this hypothesis and elucidate the precise mechanisms involved

The biology of the receptor for advanced glycation end products and its ligands[J]