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However, only allosteric site 1 was fully occupied, and site 2 may be related to crystal contact

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Only around one third of surveyed physiotherapists are applying specific tests that have been developed to combine compressive and tensile loads on the gluteal tendons, such as the FADER-R test (Hip flexion/Adduction/External Rotation + isometric internal rotation) (35%), the ADD-R test (Hip adduction in modified Obers position + isometric abduction) (38%), or the resisted external derotation test (resisted internal rotation from a position of hip flexion and external rotation) (35%)

On the other hand, other authors have shown that MPP + induces negative effects in astrocytes, such as loss of viability, impairment of energetic metabolism of mitochondria, ROS generation and decrease in the glutamate clearance by astrocytes [81,85,86]

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