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Quercetin upregulates SIRT1 and PGC-1, increases mtDNA and cytochrome c content in the muscle and brain, increases endurance performance in rodents [59], and prevents muscle atrophy in denervated mice [60], although, for example, an exercise performance is not influenced by quercetin supplementation in humans [61]

Concomitantly, we measured increased pyruvate levels in mutant compared to control cells (Supplementary Fig

Clarifying the specific interactions and signaling pathways that control antioxidant enzymes should be a primary goal of future studies

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Am J Health Syst Pharm (2010) 67:44958

Remove from the oven and carefully remove the loaf from the tin onto a wire rack