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Valenzuela A, Aspillaga M, Vial S, Guerra R (1989)

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Thus, the potential to modify intramuscular glycogen and IMT stores via diet (see above) and exercise is clear, but the corresponding effects may be variable across bodybuilders as a function of pre-contest diet (macronutrient composition and content may affect resting stores), muscle enzyme activity, and gender, among other uninvestigated variables

In addition, drug development targeting the gut-brain axis is in the exploratory phase

(early methods used colorimetric rxns for glucuronic acid) iii