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Description

W222 is rotated and pushed aside to accommodate the phenyl group of C4-10 , which is inserted deeply into the protein surrounded by W222, F225, L226, I131, M187, R183 and V127

CKD stage was based on the estimated glomerular filtration rate (GFR), determined using the CKD-EPI equation

70 , e491 (2019)

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