10.1074/mcp.M900523-MCP200 Mol
Somit stellt die Erfindung ein Stoffgemisch zur therapeutischen Behandlung des menschlichen oder tierischen Krpers zur Verfgung, das reduziertes Glutathion und mindestens eine Anthocyan-Verbindung der Gruppe Pelargonidin, Ponidin, Cyanidin, Melvidin, Petunidin, Delphinidin enthlt, wobei das reduzierte Glutathion ganz oder teilweise durch mindestens ein Thiol-Derivat des Glutathions der Gruppe Methyl-Glutathionyl-(Thio)-ther, thyl-Glutathionyl-(Thio)-ther, Mono-Acetyl-Glutathionyl-(Thio)-Ester, Mono-Phosphorsure-Glutathionyl-(Thio)-Ester ersetzt sein kann.The invention thus provides a mixture of substances for the therapeutic treatment of the human or animal body which contains reduced glutathione and at least one anthocyanin compound from the group pelargonidine, peaonidine, cyanidine, melvidin, petunidine, delphinidine, the reduced one Glutathione in whole or in part by at least one thiol derivative of the glutathione from the group methyl-glutathionyl (thio) ether, ethyl-glutathionyl (thio) ether, mono-acetyl-glutathionyl (thio) ester, monophosphoric acid Glutathionyl (thio) ester can be replaced
systematically reviewed the oxidative stress from the perspectives of oxidants and antioxidants, and noted that oxidants with vastly different half-lives may be observed at the site of generation or be transported to distant target sites where they exert oxidant activities in cell metabolism [63]
However, the elevated levels of LSH stimulate the upregulation of SCD1 expression, concurrently inhibiting lipid peroxidation and iron accumulation
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709 These indicate that proanthocyanidins promote functional recovery of SCI by inhibiting ferroptosis
