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IGF-1 DES has a 20-30 minute half-life but is about 10x more potent, making it best for localized, site-specific applications where it's injected directly into target muscles before training

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European Journal of Endocrinology (1998) 2

et al., Frontiers in Pharmacology Stacking Potential Both HGH and IGF-1 LR3 can be used as standalone compounds, but their true power often emerges in stacked protocols