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106 As a result, higher doses are often required to achieve therapeutic efficacy, which may increase the risk of adverse effects

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that methylates nicotinamide using S-adenosyl methionine (SAM)

In acute or emergency situations, this approach can be appropriate and necessary

Therefore, no company has officially initiated the NDA approval process for GHK-Cu

doi: 10.1016/S0021-9258(18)77062-2