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These findings confirm the theory that Xc-system serves as a link between inflammation and glutamate excitotoxicity and that xCT might act as a target for reducing glutamate excitotoxicity in neurodegenerative diseases under inflammation (Pampliega et al., 2011)

Those with certain genetic traits might be more sensitive

10.1167/iovs.15-16890 46 TeichmanS

Current treatment options include surgical resection, chemotherapy, and radiotherapy, but only a few patients are eligible for surgery as most are diagnosed at an advanced stage