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Romero-Herrera I, Nogales F, Gallego-Lpez MDC, Daz-Castro J, Carreras O, Ojeda ML

The advent of ARCA eliminates the interference from non-functional cap, yielding mRNA with improved stability

A-485 is a selective catalytic inhibitor of p300 that blocks histone acetylation and lactylation in preclinical models, leading to impaired cancer cell proliferation and metastasis 184

PROTAC-conjugated ADCs enable degradation of intracellular proteins beyond conventional druggable targets [561563]