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To further elucidate its mechanism in asthma-related ferroptosis, we performed virtual docking screening combined with molecular dynamics simulations, which revealed that luteolin binds effectively to ALOX15 and maintains the protein in a relatively stable conformation, thereby potentially mitigating ferroptosis in asthma by inhibiting ALOX15

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Bersuker K, Hendricks JM, Li Z, Magtanong L, Ford B, Tang PH et al (2019) The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

Which raises an important question: If youre optimizing hormones but ignoring cellular defense, are you really optimizing health

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